UK invests £9 million in fight against endemic livestock disease in flagship initiative


The investment forms part of an £11.5 million multi-phase flagship initiative to revolutionise the UK livestock sector.

The Biotechnology and Biological Sciences Research Council (BBSRC) and Department for Environment, Food and Rural Affairs (Defra) have announced £9 million funding for phase two of the ground-breaking endemic livestock disease initiative.

The £11.5 million initiative commenced in 2021 and seeks to transform the UK livestock sector by reducing the burden of endemic diseases on animal health, welfare and productivity.

Highlighting the significance of the UK livestock endemic disease challenge, the initiative is backed by key UK partners, including:

  • Defra
  • Department of Agriculture, Environment and Rural Affairs
  • Scottish Government

Developed in consultation with academia, industry and policymakers, the endemic livestock disease initiative focuses on fostering collaborative research between academia, industry and end-users.

The goal is to deliver innovative on-farm solutions that will effectively mitigate the impact of endemic diseases on the UK livestock sector.

To date, the initiative has successfully facilitated the formation of 45 new industry partnerships, forging strong collaborative networks. Moreover, it has engaged with over 170 end-users including farmers, veterinarians and policymakers to ensure that the research outcomes directly address their practical needs.

Phase two of the initiative is set to kickstart this summer, with a total of 14 ambitious projects receiving funding. These projects span the breadth of the livestock sector, encompassing:

  • pigs
  • poultry
  • beef
  • sheep
  • dairy

Of particular note is the significant emphasis on digital agriculture and machine learning, with nine of the projects incorporating cutting-edge technologies to advance disease monitoring, diagnosis and prevention.

Professor Guy Poppy, Interim Executive Chair at BBSRC, said:

Endemic diseases in the UK livestock sector pose significant challenges to animal welfare, productivity and sustainable farming practices.

By bringing together the collective expertise of academia, industry and end-users, we are confident this initiative will lead to ground-breaking advancements in disease control, fostering a healthier and more productive livestock sector.

UK Chief Veterinary Officer, Christine Middlemiss added:

The UK remains committed to working collaboratively with farmers to overcome infectious animal disease. I welcome the second phase of this exciting research initiative.

This funding brings together farmers, vets and researchers to develop and test new solutions to some of our most serious animal health challenges on farm, making a real difference to the health and wellbeing of the UK’s livestock.

The 14 pioneering projects receiving funding from phase two of the initiative represent the cutting-edge of research.

The projects harness the potential of digital technologies, advanced diagnostics and innovative vaccine development to address the challenges of endemic disease in UK livestock.

The 14 projects

Forestry by-products as novel therapeutics for parasite control in livestock

Principal investigator: Dr Spiridoula Athanasiadou, Scotland’s Rural College

Monitoring the gut microbiome via artificial intelligence (AI) and omics: a new approach to detect infection and anti-microbial resistance and support novel therapeutics in broiler precision farming

Principal investigator: Dr Tania Dottorini, University of Nottingham

AI to monitor changes in social behaviour for the early detection of disease in dairy cattle

Principal investigator: Professor Andrew Dowsey, University of Bristol

Preventing drops in egg production in UK free-range flocks: understanding the interactions between farm practices, flock coinfections and immunity

Principal investigator: Dr Kannan Ganapathy, University of Liverpool

Next generation vaccines for bovine respiratory disease complex utilising virus vaccine vectors to target both bacterial and viral pathogens

Principal investigator: Dr William Golde, Moredun Research Institute

Precision solutions for controlling fasciolosis in sheep

Principal investigator: Dr Rhys Jones, Aberystwyth University

Digital platform for sustainable health: a step change in reducing endemic disease in dairy cattle

Principal investigator: Professor Jasmeet Kaler, University of Nottingham

CO-ADAPT: adaptive management of endemic coinfections in ruminant livestock under climate change

Principal investigator: Professor Eric Morgan, Queen’s University of Belfast

A UK platform for the control of bovine viral diarrhea: application of a novel disease simulation model to guide programme development and policy design

Principal investigator: Dr Luke O’Grady, University of Nottingham

Genetic and management solutions for lameness-associated endemic diseases in dairy cattle

Principal investigator: Professor Georgios Oikonomou, University of Liverpool

Unravelling the aetiology of stunting in UK broiler flocks through the use of novel microdissection and viral meta-transcriptomic sequencing tools

Principal investigator: Dr Victoria Smyth, Agri-Food and Biosciences Institute

Protecting pigs from enzootic pneumonia: rational design of safe attenuated vaccines

Principal investigator: Professor Dirk Werling, Royal Veterinary College

Delivery of rapid diagnostic tests for sustainable control of parasitic diseases in sheep and cattle

Principal investigator: Professor Diana Williams, University of Liverpool

Effects of co-infections on Marek’s disease in poultry and development of novel recombinant Marek’s disease virus vector vaccines

Principal investigator: Dr Yongxui Yao, The Pirbright Institute

Source: UK Research and Innovation.

Launched in April 2018, UKRI is a non-departmental public body sponsored by the Department for Business, Energy and Industrial Strategy (BEIS). They bring together the seven disciplinary research councils, Research England, which is responsible for supporting research and knowledge exchange at higher education institutions in England, and the UK’s innovation agency, Innovate UK. For more details go to:

Through their five-year strategy ‘Transforming tomorrow together 2022 to 2027, UK Research and Innovation says it aims to harness the full power of the UK’s research and innovation system to tackle large-scale, complex challenges.

To do this, they have identified five strategic themes to enable working across disciplines and leveraging new and existing investment and activity.

Tackling infections is one of the themes. It will bolster national defence and response capabilities by tackling infectious diseases that pose threats to people, livestock, crops and natural resources in more integrated and innovative ways.

UKRI say endemic livestock disease initiative plays a key role in helping the UK better prepare for future disease epidemics and more effectively tackle the slow-moving pandemic of antimicrobial resistance.


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